Discovery of Polyphenolic Compounds from Mangifera indica as PotentTherapeutics for Strongyloides stercoralis Infection via Computer-aidedDrug Design
Quercetin and mangiferin emerge as promising alternatives to thiabendazole, offering favorable chemical reactivity, potent inhibition constants, and strong biological activity for the treatment of S. stercoralis.
Authors
- Ehimen Annastasia Erazua (ORCID: https://orcid.org/0000-0001-6887-6381)
- Adesoji Alani Olanrewaju (ORCID: https://orcid.org/0000-0001-6084-4465)
- Sergey Shityakov (ORCID: https://orcid.org/0000-0002-6953-9771)
- Viacheslav Kravtsov (ORCID: https://orcid.org/0000-0003-3910-5160)
- Екатерина Владимировна Скорб (ORCID: https://orcid.org/0000-0003-0888-1693)
- Oluwakemi Ebenezer (ORCID: https://orcid.org/0000-0003-1054-9665)
- Abel Kolawole Oyebamiji (ORCID: https://orcid.org/0000-0002-8932-6327)
- David O. Adekunle (ORCID: https://orcid.org/0000-0001-9458-8834)
- Omowumi Temitayo Akinola (ORCID: https://orcid.org/0000-0003-2155-4697)
- Samson Olusegun Afolabi (ORCID: https://orcid.org/0000-0002-6174-5044)
- Ayodeji Arnold Olaseinde
Institutions
- University of Alberta (CA)
- ITMO University (RU)
- University of Ibadan (NG)
- Bowen University (NG)
- Clemson University (US)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2025-03-21
- DOI
- https://doi.org/10.2174/0115734099353596250313020805
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00