Cl <sub>3</sub> Al‐PH <sub>3</sub> Is a Weak Lewis Pair Allowing the Synthesis of Sterically Highly Hindered Primary and Secondary Alkyl Phosphanes
Phosphane (PH<sub>3</sub>) gas has the highest phosphorus content of all commercial phosphorus compounds, yet its use for valuable chemicals is very limited. Aluminum chloride and phosphane yield quantitatively the adduct Cl<sub>3</sub>Al-PH<sub>3</sub>, which is easy to handle and reacts with a large set of alkyl halides to give phosphonium salts that can be converted to primary phosphanes. This sequence has been generalized to access various secondary and some tertiary phosphanes in excellent yields under mild conditions and short reaction times. With unprecedented ease, these reactions allow, in particular, the preparation of sterically demanding phosphanes, which, as ligands, are key components of highly catalytically competent transition metal complexes.
Authors
- Paul G. Pringle (ORCID: https://orcid.org/0000-0001-7250-4679)
- Norbert Weferling
- Zoltán Benkő (ORCID: https://orcid.org/0000-0001-6647-8320)
- Jan Oswald (ORCID: https://orcid.org/0000-0001-7112-5407)
- Csilla Fekete (ORCID: https://orcid.org/0000-0002-2337-6620)
- Matthew B. Baker (ORCID: https://orcid.org/0000-0003-1731-3858)
- Mark Bispinghoff (ORCID: https://orcid.org/0000-0003-1532-9805)
- Hansjörg Grützmacher
Institutions
- Sun Yat-sen University (CN)
- Board of the Swiss Federal Institutes of Technology (CH)
- Budapest University of Technology and Economics (HU)
- ETH Zurich (CH)
- University of Bristol (GB)
- Montavid Thermodynamic Research Group (HU)
- BioConsult SH (Germany) (DE)
Publication Details
- Journal
- Angewandte Chemie International Edition
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1002/anie.202501656
- Citations
- 5
- Primary Topic
- Synthesis and characterization of novel inorganic/organometallic compounds
- Type
- article
- Field-Weighted Citation Impact
- 2.69