A Case of Pancreatic Fistula Following Left Nephrectomy: A Rare Complication

Pancreatic fistula is a rare but serious complication that may arise following surgery, particularly in oncological procedures. Intraoperative pancreatic injury is an infrequent complication associated with left nephrectomy. We present the case of a 77-year-old male patient who underwent a left nephrectomy for a rare renal pelvis tumor, specifically sarcomatoid urothelial carcinoma. After two consecutive laparotomies, the patient developed a pancreatic fistula, as evidenced by excessive left drain output and elevated amylase levels in the collected fluid. The fistula was managed effectively with subcutaneous somatostatin analog (Sandostatin) injections, parenteral nutrition, and a strict nothing by mouth (NPO) regimen. This case underscores the potential risk of pancreatic fistula following radical nephrectomy, highlighting the importance of early diagnosis and appropriate management strategies. Unfortunately, the patient's recovery was complicated by intra-abdominal bleeding and septic shock, which ultimately led to his death.

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Publication Details

Journal
Cureus
Published
2025-03-25
DOI
https://doi.org/10.7759/cureus.81157
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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0.00
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article

A Case of Pancreatic Fistula Following Left Nephrectomy: A Rare Complication

Antoine Geagea, Alireza Abed, Abdelkhalick Mohammad, Fatima I Hsayan et al.
Cureus
Pancreatic and Hepatic Oncology Research
article

A Case of Pancreatic Fistula Following Left Nephrectomy: A Rare Complication

Antoine Geagea, Alireza Abed, Abdelkhalick Mohammad, Fatima I Hsayan, Sondos Naous
article en

Abstract

Pancreatic fistula is a rare but serious complication that may arise following surgery, particularly in oncological procedures. Intraoperative pancreatic injury is an infrequent complication associated with left nephrectomy. We present the case of a 77-year-old male patient who underwent a left nephrectomy for a rare renal pelvis tumor, specifically sarcomatoid urothelial carcinoma. After two consecutive laparotomies, the patient developed a pancreatic fistula, as evidenced by excessive left drain output and elevated amylase levels in the collected fluid. The fistula was managed effectively with subcutaneous somatostatin analog (Sandostatin) injections, parenteral nutrition, and a strict nothing by mouth (NPO) regimen. This case underscores the potential risk of pancreatic fistula following radical nephrectomy, highlighting the importance of early diagnosis and appropriate management strategies. Unfortunately, the patient's recovery was complicated by intra-abdominal bleeding and septic shock, which ultimately led to his death.

CureusVol. 17(3)
Lebanese University (LB)
Zero hunger
Openalex Percentile: Top 92%
Pancreatic and Hepatic Oncology Research
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A Case of Pancreatic Fistula Following Left Nephrectomy: A Rare Complication — Antoine Geagea, Alireza Abed, et al. · Cureus (2025) | TGRS Research Map | TGRS