Mycoidesin, a novel lantibiotic, exhibits potent bacteriostatic activity against <i>Listeria monocytogenes</i> and effectively controls its growth in beef
This study aimed to identify highly effective, stable, and safe natural bacteriocin preservatives with anti-<i>Listeria monocytogenes</i> activity. We isolated a novel class II lantibiotic, mycoidesin, which exhibited more efficient bacteriostatic activity against <i>L. monocytogenes</i> and increased stability compared to the applied bacteriocin food preservative, nisin A. Mycoidesin also showed favorable biosafety. Moreover, mycoidesin could be effectively used for controlling <i>L. monocytogenes</i> in beef, demonstrating its potential as a biopreservative to prevent <i>L. monocytogenes</i>-related contamination and improve the safety of meat and meat products in the agricultural and food industries.
Authors
- Xin Zeng (ORCID: https://orcid.org/0000-0002-9708-5594)
- Congcong Xu (ORCID: https://orcid.org/0000-0002-3133-6928)
- Jiajia Ding
- Mengyu Gao (ORCID: https://orcid.org/0000-0003-1385-7364)
- Shulin Deng (ORCID: https://orcid.org/0000-0002-7231-3415)
- Shu Liu (ORCID: https://orcid.org/0009-0000-2914-1091)
- Hualin Liu (ORCID: https://orcid.org/0000-0002-3630-5522)
- Guoqiang Huang (ORCID: https://orcid.org/0000-0003-3900-399X)
- Bingyue Xin (ORCID: https://orcid.org/0000-0001-5690-3522)
- Fei Zhang (ORCID: https://orcid.org/0000-0002-7099-4130)
- Wen-Cheng Lv
Institutions
- Huaibei Normal University (CN)
- Qufu Normal University (CN)
- Huazhong Agricultural University (CN)
Publication Details
- Journal
- Applied and Environmental Microbiology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1128/aem.00067-25
- Citations
- 2
- Primary Topic
- Essential Oils and Antimicrobial Activity
- Type
- article
- Field-Weighted Citation Impact
- 2.32
Funders
- National Natural Science Foundation of China