The Global Leadership Initiative on Malnutrition (GLIM) inflammation criteria to predict survival in patients with advanced cancer: A prospective cohort study
Systemic inflammation, as assessed by CRP, mGPS and NLR, significantly improves the relationship between phenotypic criteria and OS. These findings support the GLIM framework's inclusion of systemic inflammation as a critical factor. Given its strong predictive value, systemic inflammation should be prioritized in routine clinical assessments of cancer patients, with mGPS having greater prognostic value within the GLIM framework.
Authors
- Barry J. A. Laird (ORCID: https://orcid.org/0000-0002-2807-6192)
- Ross D. Dolan (ORCID: https://orcid.org/0000-0002-5272-5906)
- Aoife M. Ryan (ORCID: https://orcid.org/0000-0003-4330-9705)
- Marie Fallon (ORCID: https://orcid.org/0000-0001-9214-0091)
- Josh McGovern (ORCID: https://orcid.org/0000-0002-6889-6240)
- Chattarin Pumtako (ORCID: https://orcid.org/0000-0002-7754-7229)
- Derek G. Power (ORCID: https://orcid.org/0000-0001-6763-0005)
- Claribel Pl Simmons
- E.S. Sullivan (ORCID: https://orcid.org/0000-0001-8343-3415)
- Donald C. McMillan (ORCID: https://orcid.org/0000-0003-4260-5334)
Institutions
- University College Cork (IE)
- Edinburgh Cancer Research (GB)
- University of Glasgow (GB)
Publication Details
- Journal
- Clinical Nutrition ESPEN
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1016/j.clnesp.2025.03.027
- Citations
- 3
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 3.49