Associations of maternal cyclin-dependent kinase 5 regulatory subunit-associated protein 1-like 1(CDKAL1) gene variants with adverse pregnancy outcome in Chinese women
The maternal CDKAL1 gene variants were associated with increased risk of adverse pregnancy outcome, low birth weight and macrosomia, independent of gestational diabetes mellitus. CDKAL1 gene might be a useful marker for identification of individuals at a particularly high risk of adverse pregnancy outcome in early pregnancy.
Authors
- Zhijie Yu (ORCID: https://orcid.org/0000-0002-4901-3545)
- Yijuan Qiao (ORCID: https://orcid.org/0000-0001-5570-5188)
- Xilin Yang (ORCID: https://orcid.org/0000-0002-9462-7992)
- Shuaijun Yue (ORCID: https://orcid.org/0009-0004-8145-4334)
- Gang Hu (ORCID: https://orcid.org/0000-0002-6172-8017)
- Jin Liu (ORCID: https://orcid.org/0000-0003-1063-9791)
- Jing Li (ORCID: https://orcid.org/0000-0003-2777-2572)
- Tao Zhang (ORCID: https://orcid.org/0000-0001-8407-4717)
- Zihao Zhang (ORCID: https://orcid.org/0000-0001-5106-2656)
- Jun Ma (ORCID: https://orcid.org/0000-0003-3529-1808)
- Hui Wang (ORCID: https://orcid.org/0000-0003-2902-5570)
- Weiqin Li (ORCID: https://orcid.org/0000-0001-5011-7985)
- Meng Su (ORCID: https://orcid.org/0000-0001-6255-3629)
- Junhong Leng (ORCID: https://orcid.org/0000-0002-8450-6329)
Institutions
- Pennington Biomedical Research Center (US)
- Dalhousie University (CA)
- Tianjin Children's Hospital (CN)
- Tianjin Medical University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1186/s12884-025-07418-1
- Primary Topic
- Gestational Diabetes Research and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00