Screening and exploration of neoadjuvant “de-escalation” therapy for early breast cancer
Patients with operable cStage II-IIIA breast cancer who achieved pCR after a short period of neoadjuvant chemotherapy have a satisfactory prognosis and may be suitable for chemotherapy "de-escalation." This approach is also a dominant application of neoadjuvant "tailoring therapy."
Authors
- Bingqi Xu
- Zhenfeng Huang (ORCID: https://orcid.org/0000-0001-9179-5272)
- Xinhang Liu (ORCID: https://orcid.org/0009-0003-0494-4877)
- Li Song (ORCID: https://orcid.org/0000-0001-9078-5742)
- Fei Gao (ORCID: https://orcid.org/0000-0002-4086-2575)
- Nana Zhang (ORCID: https://orcid.org/0009-0002-7172-9221)
- Abiyasi Nanding (ORCID: https://orcid.org/0000-0002-8343-0721)
- Jiawei Zhang (ORCID: https://orcid.org/0000-0001-5127-9142)
- Peng Zhang (ORCID: https://orcid.org/0009-0001-1880-3544)
- Guoqiang Zhang (ORCID: https://orcid.org/0000-0003-0771-7533)
- Jian Zhang (ORCID: https://orcid.org/0000-0001-7217-0111)
- Mingyang Liu (ORCID: https://orcid.org/0000-0002-7427-2709)
- Rui Li (ORCID: https://orcid.org/0000-0001-7857-9735)
- Wenli Kang (ORCID: https://orcid.org/0000-0002-5976-4190)
- Ming Shan (ORCID: https://orcid.org/0000-0002-9495-1645)
- Qi Jiang (ORCID: https://orcid.org/0009-0009-5834-0968)
- Zibo Shen
Institutions
- Jiamusi University (CN)
- Harbin Medical University (CN)
- Shenzhen University (CN)
- King's College London (GB)
- First Affiliated Hospital of Heilongjiang University of Chinese Medicine (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Daqing Oilfield General Hospital (CN)
- Dalian Municipal Central Hospital (CN)
- Baotou Teachers College (CN)
- Qujiang People's Hospital (CN)
- Shenzhen Third People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3389/fphar.2025.1574665
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00