ULTRAFAST AND ULTRAPARALLEL PICOLITER PARTITIONING OF DIFFERENT REACTION MIXES BY CENTRIFUGAL MICROFLUIDIC ARRAY TECHNOLOGY (CM-ART)
We present the centrifugal microfluidic array technology, CM-ArT, capable of ultrafast and ultraparallel liquid partitioning of a reaction mix into 3.8 million reaction wells in less than 90 seconds, achieving a dynamic range exceeding 6 logs for digital assays.CM-ArT ensures uniform well filling for various reaction mixes without the need for manufacturer-specific reagent formulations, creating a versatile platform for digital assays.
Authors
- Martina Heyer (ORCID: https://orcid.org/0000-0002-5522-9027)
- Fabian Lickert (ORCID: https://orcid.org/0000-0001-7729-5976)
- Peter Juelg (ORCID: https://orcid.org/0000-0003-1448-9831)
- Tobias Hutzenlaub (ORCID: https://orcid.org/0000-0001-6554-0604)
- Nils Paust (ORCID: https://orcid.org/0000-0003-0890-3709)
- Sohiful Anuar Zainol Murad (ORCID: https://orcid.org/0000-0001-9412-5119)
- Helena Gmoser
Publication Details
- Published
- 2024-10-07
- DOI
- https://doi.org/10.70477/gfpt1768
- Primary Topic
- Microfluidic and Capillary Electrophoresis Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00