Cholesteryl Ester Species but Not Serum Proprotein Convertase Subtilisin/Kexin Type 9 Levels Decline in Male Patients with Active Inflammatory Bowel Disease
In active IBD, a reduction in FC and almost all CE species was observed only in males, while serum PCSK9 levels remained within normal ranges in both sexes. It can be hypothesized that blocking PCSK9 may further reduce serum cholesterol levels, which may have adverse effects in male patients with active IBD.
Authors
- Hauke Christian Tews (ORCID: https://orcid.org/0009-0001-1068-2151)
- A. Hettenbach
- Marcus Höring (ORCID: https://orcid.org/0000-0002-3651-392X)
- Tanja Elger
- Gerhard Liebisch (ORCID: https://orcid.org/0000-0003-4886-0811)
- Christa Buechler (ORCID: https://orcid.org/0000-0002-5635-3994)
- Johanna Loibl
- Martina Müller (ORCID: https://orcid.org/0000-0002-8520-4568)
- Arne Kandulski (ORCID: https://orcid.org/0009-0005-9065-8395)
- Muriel Huss
Institutions
- University Hospital Regensburg (DE)
Publication Details
- Journal
- Pathophysiology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3390/pathophysiology32020013
- Citations
- 3
- Primary Topic
- Inflammatory Bowel Disease
- Type
- article
- Field-Weighted Citation Impact
- 5.45