Kynurenine amplifies tetrahydrocannabinol-induced sensorimotor impairment and classic “tetrad” effects in mice
The present data indicate for the first time that KYN amplifies the THC-induced sensorimotor impairment and classic "tetrad" response possibly through a pharmacokinetic interaction.
Authors
- Sabrine Bilel (ORCID: https://orcid.org/0000-0003-1515-980X)
- Sarah Beggiato (ORCID: https://orcid.org/0000-0002-8826-7556)
- Stefano Comai (ORCID: https://orcid.org/0000-0002-5686-7194)
- Giorgia Corli (ORCID: https://orcid.org/0000-0002-2973-2446)
- Matteo Marti (ORCID: https://orcid.org/0000-0001-8751-2882)
- Stefano Dall’Acqua (ORCID: https://orcid.org/0000-0001-8264-6953)
- Luca Ferraro (ORCID: https://orcid.org/0000-0003-2390-6414)
- Edoardo Tiziani
- Daniele Chirenti
Institutions
- University of Padua (IT)
- University of Ferrara (IT)
Publication Details
- Journal
- Progress in Neuro-Psychopharmacology and Biological Psychiatry
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1016/j.pnpbp.2025.111342
- Citations
- 3
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.73