Epigenetic ALYREF/UHRF1/RHOB Axis in Corneal Wound Healing and Implications for Epithelial Tumorigenesis
Our study identifies a novel epigenetic ALYREF/UHRF1/RHOB axis that enhances CEWH. Importantly, this axis appears to be conserved across various epithelial-derived tumors, suggesting its broader biological significance.
Authors
- Dongsheng Yan (ORCID: https://orcid.org/0000-0003-0551-2219)
- Guangying Luo (ORCID: https://orcid.org/0000-0003-1400-2130)
- Peter S. Reinach (ORCID: https://orcid.org/0000-0002-3494-4523)
- Qiongjie Cao
- Sheng-Hong Lan
- Yong Lin (ORCID: https://orcid.org/0000-0001-5921-3404)
- Weiwei Xu (ORCID: https://orcid.org/0000-0001-8310-2632)
- Xiaohong Chen (ORCID: https://orcid.org/0000-0002-9797-8384)
- Hua Zhang (ORCID: https://orcid.org/0000-0001-5045-8739)
- Jiao Wang (ORCID: https://orcid.org/0000-0002-4998-8748)
- Disuo Ren
Institutions
- Wenzhou Medical University (CN)
- First Affiliated Hospital of Wenzhou Medical University (CN)
- Affiliated Eye Hospital of Wenzhou Medical College (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1167/iovs.66.3.54
- Citations
- 2
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.72