The Spatial Transcriptomic Atlas of Human Limbus and Vital Niche Microenvironment Regulating the Fate of Limbal Epithelial Stem Cells
This research mapped the spatial positioning of key cells within the limbal niche and detailed interactions between major cell types. These findings provide a foundation for further LESC research and enhance our understanding of corneal biology.
Authors
- Yao Fu (ORCID: https://orcid.org/0000-0002-3389-8211)
- Liangbo Chen (ORCID: https://orcid.org/0000-0002-7777-0877)
- Fei Fang (ORCID: https://orcid.org/0000-0003-0829-9871)
- Junzhao Chen
- Hao Sun
- Siyi Zhang (ORCID: https://orcid.org/0000-0002-7730-9546)
- Shiding Li
- Chunyi Shao
Institutions
- Shanghai Jiao Tong University (CN)
- Shanghai Ninth People's Hospital (CN)
- Shanghai Institute of Hematology (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1167/iovs.66.3.52
- Citations
- 1
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 0.81