Pentosan polysulfate alleviates interstitial cystitis/bladder pain syndrome by modulating bile acid metabolism and activating the TGR5 receptor through gut microbiota regulation
PPS exerts its protective effects against IC/BPS by modulating the gut microbiome and its metabolites.
Authors
- Yu Yao (ORCID: https://orcid.org/0000-0002-0089-9568)
- Wentai Shangguan (ORCID: https://orcid.org/0000-0001-8103-9078)
- Jingwen Xue (ORCID: https://orcid.org/0009-0000-9957-5549)
- Benlin Wang (ORCID: https://orcid.org/0000-0002-8358-3154)
- Ming Xie
- Peng Wu (ORCID: https://orcid.org/0000-0003-2676-508X)
- Qi Sun (ORCID: https://orcid.org/0000-0003-4379-2442)
- Zhengyuan Feng
- Yuexuan Zhu
- Zhangrui Zhu
Institutions
- Nanfang Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Bladder
- Published
- 2025-03-24
- DOI
- https://doi.org/10.14440/bladder.2024.0060
- Primary Topic
- Urinary Bladder and Prostate Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00