Adipose tissue loss during neoadjuvant chemotherapy: a key prognostic factor in advanced epithelial ovarian cancer
Our findings suggests that early and substantial loss of visceral adipose tissue during NAC is a significant predictor of poor survival in advanced EOC. This highlights an urgent need for targeted nutritional or pharmaceutical strategies to mitigate fat loss and improve patients outcomes.
Authors
- Stéphane Servais (ORCID: https://orcid.org/0000-0002-3127-9679)
- Caroline Goupille (ORCID: https://orcid.org/0000-0002-0177-0926)
- Christophe Vandier (ORCID: https://orcid.org/0000-0003-2559-0660)
- A. Bleuzen
- Adeline Dolly (ORCID: https://orcid.org/0000-0002-6878-0168)
- Lobna Ouldamer (ORCID: https://orcid.org/0000-0001-9465-0335)
- Jean‐François Dumas (ORCID: https://orcid.org/0000-0002-2293-6606)
- Wassim Benouali
Institutions
- Université de Tours (FR)
- Inserm (FR)
- Centre Hospitalier Universitaire de Tours (FR)
- Hôpital Bretonneau (FR)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3389/fphys.2025.1537484
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16