Identification of autophagy-related immune targets for enhancing immunotherapy in pancreatic cancer aggressiveness
This study introduces a novel prognostic model incorporating five ARGs, highlighting their potential as immune targets for cancer immunotherapy. The negative correlation between RHEB and LC3 suggests a therapeutic pathway for PCM intervention, laying the groundwork for more effective anti-cancer strategies. These findings advance the identification of novel immune targets and signaling pathways, aligning with precision medicine goals in cancer treatment.
Authors
- Linju Wu (ORCID: https://orcid.org/0000-0003-4190-0075)
- Jin He (ORCID: https://orcid.org/0000-0001-9698-1816)
- Zheng Jiang (ORCID: https://orcid.org/0000-0002-1440-6840)
- Fan Wu (ORCID: https://orcid.org/0000-0002-5071-0882)
- Quantong Deng (ORCID: https://orcid.org/0000-0002-6782-7577)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1007/s12672-025-02190-2
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 1.35