Hemin as a protective agent in an in vitro model of hypoxia/reoxygenation-induced injury
The findings suggest that low-dose, short-term hemin pretreatment can effectively reduce hypoxia/reoxygenation-induced cellular damage in cardiomyocytes through the upregulation of heme oxygenase-1. These results underscore the therapeutic potential of hemin in attenuating myocardial hypoxia/reoxygenation injury.
Authors
- Zuoyan Wang (ORCID: https://orcid.org/0009-0002-7004-6138)
- Wei Liu (ORCID: https://orcid.org/0000-0002-0953-7838)
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Beijing Jishuitan Hospital (CN)
Publication Details
- Journal
- SAGE Open Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1177/20503121251329163
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 0.00