Aurantio-obtusin improves obesity and protects hepatic inflammation by rescuing mitochondrial damage in overwhelmed brown adipose tissue
AO not only improves thermogenesis and mitochondrial function of BAT but also prevents liver inflammation by repairing mitochondrial function and blocking the transfer of mtDNA from BAT to the liver.
Authors
- Ruiyu Wu (ORCID: https://orcid.org/0000-0003-3357-7925)
- Xiaoyong Xue (ORCID: https://orcid.org/0000-0001-9001-4569)
- Fanghong Li (ORCID: https://orcid.org/0000-0001-6793-7605)
- Lingling Qin (ORCID: https://orcid.org/0000-0003-0610-3943)
- Runping Liu (ORCID: https://orcid.org/0000-0001-8873-5252)
- Yinhao Zhang
- Jiaorong Qu
- Chen Wang (ORCID: https://orcid.org/0000-0003-2322-5758)
- Yijie Li (ORCID: https://orcid.org/0000-0001-7551-117X)
- Xiaojiaoyang Li (ORCID: https://orcid.org/0000-0002-8997-9651)
- Ranyun Chen
Institutions
- Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1186/s13020-025-01097-y
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00