Fedratinib-Associated Uveitis Effectively Treated With Sub-Tenon's Triamcinolone Acetonide Injection: A Case Report

This report describes the case of uveitis in a 74-year-old woman with myelofibrosis who was treated with fedratinib. Both her eyes had hyperemia, anterior chamber cells, keratic precipitates, and vitritis. Based on her clinical history, negative clinical examination findings (except for diabetes), and fedratinib treatment, she was diagnosed with fedratinib-induced uveitis. Subsequently, the patient received sub-Tenon's triamcinolone acetonide (STA) injection in both eyes. The next day, her subjective symptoms were alleviated. Moreover, her objective symptoms were deemed to have improved after the examination performed after a few days. STA injection was extremely effective for treating fedratinib-induced uveitis.

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Journal
Cureus
Published
2025-03-25
DOI
https://doi.org/10.7759/cureus.81184
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
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article

Fedratinib-Associated Uveitis Effectively Treated With Sub-Tenon's Triamcinolone Acetonide Injection: A Case Report

Erina Daizumoto, Akira Saitoh, A Saitoh, Yukiko Nagahara
Cureus
Sarcoidosis and Beryllium Toxicity Research
article

Fedratinib-Associated Uveitis Effectively Treated With Sub-Tenon's Triamcinolone Acetonide Injection: A Case Report

Erina Daizumoto, Akira Saitoh, A Saitoh, Yukiko Nagahara
article en

Abstract

This report describes the case of uveitis in a 74-year-old woman with myelofibrosis who was treated with fedratinib. Both her eyes had hyperemia, anterior chamber cells, keratic precipitates, and vitritis. Based on her clinical history, negative clinical examination findings (except for diabetes), and fedratinib treatment, she was diagnosed with fedratinib-induced uveitis. Subsequently, the patient received sub-Tenon's triamcinolone acetonide (STA) injection in both eyes. The next day, her subjective symptoms were alleviated. Moreover, her objective symptoms were deemed to have improved after the examination performed after a few days. STA injection was extremely effective for treating fedratinib-induced uveitis.

CureusVol. 17(3)
Takamatsu University (JP), Takamatsu Red Cross Hospital (JP), Nishi Eye Hospital (JP)
Openalex Percentile: Top 93%
Sarcoidosis and Beryllium Toxicity Research
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Fedratinib-Associated Uveitis Effectively Treated With Sub-Tenon's Triamcinolone Acetonide Injection: A Case Report — Erina Daizumoto, Akira Saitoh, et al. · Cureus (2025) | TGRS Research Map | TGRS