Microstructural Characterization, Cytotoxicity and Antibacterial Evaluation of Multicomponent MoNbNiTiZr Alloy

Traditional biomaterials like CoCrMo, Ti, and stainless-steel face challenges due to their instability in biological settings. As an alternative, exploring multicomponent alloys is viewed as a viable path for bettering both mechanical performance and biocompatibility. Our research explores the potentiality of the MoNbNiTiZr based alloy for biomedical applications. The microstructural characterization was realized using X-Ray Diffractometry (XRD) and Scanning Electron Microscopy (SEM/EDS). We also conducted Vickers microhardness tests and assessed it’s in vitro biocompatibility and antibacterial action against S. aureus and S. aureus HU25 strains relative to cp-Ti. Our observations denote that this alloy showcases a triphasic structure, consisting of dendritic and interdendritic zones with BCC, HCP, and Laves formations. A microhardness of is approximately 576.5 HV align with values for comparable multicomponent alloys in the biomedical field. Pertaining to its antibacterial efficiency and in vitro compatibility, this alloy manifests commendable antibacterial performance and relevant compatibility in comparison with cp-Ti.

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Publication Details

Journal
Materials Research
Published
2025-01-01
DOI
https://doi.org/10.1590/1980-5373-mr-2024-0348
Primary Topic
Titanium Alloys Microstructure and Properties
Type
article
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article

Microstructural Characterization, Cytotoxicity and Antibacterial Evaluation of Multicomponent MoNbNiTiZr Alloy

Daniel Bragança Viana, Antonio Augusto Araújo Pinto da Silva, Daniel Crístian Ferreira Soares, Daniela Sachs et al.
Materials Research
Titanium Alloys Microstructure and Properties
article

Microstructural Characterization, Cytotoxicity and Antibacterial Evaluation of Multicomponent MoNbNiTiZr Alloy

Daniel Bragança Viana, Antonio Augusto Araújo Pinto da Silva, Daniel Crístian Ferreira Soares, Daniela Sachs, Leandro Bernardes Serrano, Thiago Gonçalves de Oliveira, Grazielle Aparecida dos Santos, Sebastião Bruno Vilas Boas
article en

Abstract

Traditional biomaterials like CoCrMo, Ti, and stainless-steel face challenges due to their instability in biological settings. As an alternative, exploring multicomponent alloys is viewed as a viable path for bettering both mechanical performance and biocompatibility. Our research explores the potentiality of the MoNbNiTiZr based alloy for biomedical applications. The microstructural characterization was realized using X-Ray Diffractometry (XRD) and Scanning Electron Microscopy (SEM/EDS). We also conducted Vickers microhardness tests and assessed it’s in vitro biocompatibility and antibacterial action against S. aureus and S. aureus HU25 strains relative to cp-Ti. Our observations denote that this alloy showcases a triphasic structure, consisting of dendritic and interdendritic zones with BCC, HCP, and Laves formations. A microhardness of is approximately 576.5 HV align with values for comparable multicomponent alloys in the biomedical field. Pertaining to its antibacterial efficiency and in vitro compatibility, this alloy manifests commendable antibacterial performance and relevant compatibility in comparison with cp-Ti.

Materials ResearchVol. 28
Universidade Federal de Itajubá (BR)
Openalex Percentile: Top 96%
Titanium Alloys Microstructure and Properties
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Microstructural Characterization, Cytotoxicity and Antibacterial Evaluation of Multicomponent MoNbNiTiZr Alloy — Daniel Bragança Viana, Antonio Augusto Araújo Pinto da Silva, et al. · Materials Research (2025) | TGRS Research Map | TGRS