Acupuncture regulates α-synuclein expression via <i>serping1</i> in an MPTP-induced mouse model of Parkinsonism

Our results suggest that an MPTP-induced reduction in <i>serping1</i> level leads to decreased TH and increased α-syn expression, and that these effects can be attenuated/blocked by acupuncture at GB34 and LR3. Our findings provide new evidence for the neuroprotective effects of acupuncture on dopaminergic cells, which may be mediated by control of <i>serping1</i> expression.

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Publication Details

Journal
Acupuncture in Medicine
Published
2025-03-25
DOI
https://doi.org/10.1177/09645284251327195
Primary Topic
Parkinson's Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Acupuncture regulates α-synuclein expression via serping1 in an MPTP-induced mouse model of Parkinsonism

Min Hyung Seo, Sujung Yeo
Acupuncture in Medicine
Parkinson's Disease Mechanisms and Treatments
article

Acupuncture regulates α-synuclein expression via serping1 in an MPTP-induced mouse model of Parkinsonism

Min Hyung Seo, Sujung Yeo
article en

Abstract

Our results suggest that an MPTP-induced reduction in <i>serping1</i> level leads to decreased TH and increased α-syn expression, and that these effects can be attenuated/blocked by acupuncture at GB34 and LR3. Our findings provide new evidence for the neuroprotective effects of acupuncture on dopaminergic cells, which may be mediated by control of <i>serping1</i> expression.

Acupuncture in MedicineVol. 43(2)
Sangji University (KR)
Good health and well-being
Openalex Percentile: Top 91%
Parkinson's Disease Mechanisms and Treatments
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