A head-to-head comparison of S100B and GFAP/UCH-L1 for detection of traumatic intracranial lesions in a Scandinavian trauma cohort
In this study, S100B and GFAP/UCH-L1 had an almost perfect agreement for classification of mTBI patients and comparable diagnostic performances for detecting traumatic intracranial lesions. Our results therefore support GFAP/UCH-L1 as a feasible alternative to S100B for detecting traumatic intracranial lesions in mTBI.
Authors
- Kirsten Duch (ORCID: https://orcid.org/0000-0002-5984-5134)
- Abdolreza Babaee (ORCID: https://orcid.org/0000-0002-9848-5442)
- Claus Vinter Bødker Hviid (ORCID: https://orcid.org/0000-0003-1740-7555)
- Ole Brink (ORCID: https://orcid.org/0000-0003-1956-2970)
- Thea Overgaard Wichmann (ORCID: https://orcid.org/0000-0002-1838-1345)
- Mikkel Mylius Rasmussen (ORCID: https://orcid.org/0000-0002-4768-7255)
- Lars C. Borris (ORCID: https://orcid.org/0000-0002-0527-1518)
- Maj Lesbo
Institutions
- Aarhus University (DK)
- Aalborg University Hospital (DK)
- Aarhus University Hospital (DK)
- Regionshospitalet Viborg (DK)
- Aalborg University (DK)
Publication Details
- Journal
- Scandinavian Journal of Trauma Resuscitation and Emergency Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1186/s13049-025-01364-9
- Citations
- 10
- Primary Topic
- Traumatic Brain Injury and Neurovascular Disturbances
- Type
- article
- Field-Weighted Citation Impact
- 13.89