Antiviral activity of Scutellaria baicalensis Georgi Extract against Getah virus in vivo and in vitro

The experimental findings demonstrate that ESG exhibits significant antiviral efficacy against GETV infection both <i>in vitro</i> and <i>in vivo</i>. These results indicate that ESG represents a promising therapeutic candidate for the prevention and treatment of GETV infections. Mechanistically, the antiviral activity of ESG appears to be mediated, at least in part, through the modulation of E2 protein expression.