Derivation and validation of a non-invasive optoacoustic imaging biomarker for detection of patients with intermittent claudication
Post-exercise MSOT-derived saturation in the calf muscle is validated as a non-invasive imaging biomarker to distinguish HV and IC patients yielding high sensitivity and specificity.
Authors
- Wolfgang Uter (ORCID: https://orcid.org/0000-0002-4498-3710)
- J. Günther (ORCID: https://orcid.org/0000-0003-2731-9524)
- Werner Lang (ORCID: https://orcid.org/0000-0003-4114-7589)
- Anna P. Träger
- Christian‐Alexander Behrendt (ORCID: https://orcid.org/0000-0003-0406-3319)
- Maximilian J. Waldner (ORCID: https://orcid.org/0000-0002-5560-7665)
- Markus F. Neurath (ORCID: https://orcid.org/0000-0003-4344-1474)
- Adrian P. Regensburger (ORCID: https://orcid.org/0000-0001-8244-1261)
- Ferdinand Knieling (ORCID: https://orcid.org/0000-0002-3535-2626)
- Roman Raming
- Yi Li (ORCID: https://orcid.org/0000-0001-8385-4711)
- Ulrich Rother (ORCID: https://orcid.org/0000-0002-4016-5673)
- Alexandra L. Wagner (ORCID: https://orcid.org/0000-0001-6673-358X)
- Alexander Meyer (ORCID: https://orcid.org/0000-0002-8976-8985)
- Lars‐Philip Paulus
- Adrian Büehler
- Joachim Woelfle (ORCID: https://orcid.org/0000-0002-9132-6174)
- Michael Uder (ORCID: https://orcid.org/0000-0001-6238-4247)
- Milenko Caranovic
- Julius Kempf (ORCID: https://orcid.org/0000-0002-7036-6310)
Institutions
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- University of Münster (DE)
- Universitätsklinikum Erlangen (DE)
- MSH Medical School Hamburg – University of Applied Sciences and Medical University (DE)
- Asklepios Fachklinikum Brandenburg (DE)
- University Hospital Münster (DE)
Publication Details
- Journal
- Communications Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1038/s43856-025-00801-1
- Citations
- 1
- Primary Topic
- Peripheral Artery Disease Management
- Type
- article
- Field-Weighted Citation Impact
- 2.01