ZBTB6 promotes breast cancer progression by inhibiting ARHGAP6 transcription and modulating the STAT3 signaling pathway
These findings suggest that ZBTB6 promotes breast cancer progression by repressing the transcription of ARHGAP6 and activating the STAT3 signaling pathway. Consequently, ZBTB6 may serve as a potential prognostic biomarker or therapeutic target for breast cancer patients.
Authors
- Na Hao
- Chaowei Deng (ORCID: https://orcid.org/0000-0003-0918-2675)
- Shengyu Pu (ORCID: https://orcid.org/0000-0002-8121-4507)
- Yudong Zhou (ORCID: https://orcid.org/0000-0002-6364-3869)
- Qi Zheng (ORCID: https://orcid.org/0000-0002-2582-1222)
- Yang Liu (ORCID: https://orcid.org/0000-0002-0972-8511)
- Xiaojiang Tang
Institutions
- Shaanxi Provincial People's Hospital (CN)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1186/s12967-025-06364-y
- Citations
- 1
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- Natural Science Basic Research Program of Shaanxi Province