Clinical Value of MLPA for Prognostic Assessment of Chromosomal Rearrangements and DNA Methylation in Uveal Melanoma
Although MLPA effectively identifies CNVs relevant to UM prognosis, integrating additional methylation-specific approaches could broaden the scope of DNA methylation analysis, offering a more comprehensive molecular understanding of UM that may enhance prognostication and personalized treatment.
Authors
- Andrej Ficek (ORCID: https://orcid.org/0000-0001-7526-2361)
- Ivana Kašubová (ORCID: https://orcid.org/0000-0003-2938-0855)
- Marek Samec (ORCID: https://orcid.org/0000-0002-2545-7694)
- Zuzana Daňková (ORCID: https://orcid.org/0000-0003-4761-7553)
- Jela Valášková
- Viera Horváthová Kajabová (ORCID: https://orcid.org/0000-0002-7081-0602)
- Alena Furdová (ORCID: https://orcid.org/0000-0001-5689-892X)
- Martina Pecimonova
- Božena Smolková (ORCID: https://orcid.org/0000-0002-4906-5652)
- Lucia Demková
- Andrea Šoltýsová (ORCID: https://orcid.org/0000-0002-1402-3583)
- Pavel Babál (ORCID: https://orcid.org/0000-0001-8170-1850)
- Dana Dvorská (ORCID: https://orcid.org/0009-0000-1080-6460)
Institutions
- Cancer Research Institute of the Slovak Academy of Sciences (SK)
- Biomedical Research Center of the Slovak Academy of Sciences (SK)
- Comenius University Bratislava (SK)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1167/iovs.66.3.51
- Citations
- 1
- Primary Topic
- Ocular Oncology and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Ministerstvo školstva, vedy, výskumu a športu Slovenskej republiky
- Agentúra na Podporu Výskumu a Vývoja
- Vedecká Grantová Agentúra MŠVVaŠ SR a SAV