Fate of Residual Patch Leak After Surgical Closure of Congenital Perimembranous Ventricular Septal Defects

IntroductionVentricular septal defects (VSDs) account for 50% of congenital heart defects in children. Surgical closure of moderate to large VSDs using patch material is considered the standard treatment in children to prevent future complications.ObjectivesWe evaluated the fate of VSD patch leak and its impact on aortic and tricuspid valve regurgitation at one year after surgery.MethodsThis retrospective study consisted of patients with a perimembranous VSD who underwent surgery between January 2016 and July 2021. Demographic, echocardiographic, clinical, and operative data were retrospectively reviewed. All patients' echocardiographic images were analyzed at discharge, 6, and 12 months after surgery. Echocardiography assessment focused on the degree of residual VSD (rVSD) patch leak and aortic and tricuspid regurgitation grade compared with preoperative echocardiography.ResultsSeventy-one consecutive patients who underwent perimembranous VSD surgical closure were reviewed. No patient required reintervention. There was one early mortality during follow-up. Of the 70 patients with complete follow-up, 24 patients (34.33%) had a 1-2 mm rVSD patch leak and 4 patients (5.7%) had a 2-3 mm rVSD patch leak at the time of discharge. At 12-month follow-up echocardiography, 67 patients (95.7%) had no rVSD patch leak. Aortic and tricuspid valve regurgitation significantly improved from discharge to 12 months after surgery. The size of the patch leak did not affect patients' weight gain (<i>P</i> ≥ .05).ConclusionsWe demonstrated that a 2 mm or less rVSD patch leak is benign, has no impact on tricuspid or aortic valve function, no impact on weight gain, and almost always decreases in severity or disappears.

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Publication Details

Journal
World Journal for Pediatric and Congenital Heart Surgery
Published
2025-03-25
DOI
https://doi.org/10.1177/21501351251314387
Primary Topic
Congenital Heart Disease Studies
Type
article
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article

Fate of Residual Patch Leak After Surgical Closure of Congenital Perimembranous Ventricular Septal Defects

Hani N. Mufti, Luis Zerpa Acosta, Alfredo Gamboa, Arwa A Alrrzqi et al.
World Journal for Pediatric and Congenital Heart Surgery
Congenital Heart Disease Studies
article

Fate of Residual Patch Leak After Surgical Closure of Congenital Perimembranous Ventricular Septal Defects

Hani N. Mufti, Luis Zerpa Acosta, Alfredo Gamboa, Arwa A Alrrzqi, Ysmeen T. Bucklain, Ahmed Qumsani, Sereen Kazim, Abdulaziz M. Shaheen
article en

Abstract

IntroductionVentricular septal defects (VSDs) account for 50% of congenital heart defects in children. Surgical closure of moderate to large VSDs using patch material is considered the standard treatment in children to prevent future complications.ObjectivesWe evaluated the fate of VSD patch leak and its impact on aortic and tricuspid valve regurgitation at one year after surgery.MethodsThis retrospective study consisted of patients with a perimembranous VSD who underwent surgery between January 2016 and July 2021. Demographic, echocardiographic, clinical, and operative data were retrospectively reviewed. All patients' echocardiographic images were analyzed at discharge, 6, and 12 months after surgery. Echocardiography assessment focused on the degree of residual VSD (rVSD) patch leak and aortic and tricuspid regurgitation grade compared with preoperative echocardiography.ResultsSeventy-one consecutive patients who underwent perimembranous VSD surgical closure were reviewed. No patient required reintervention. There was one early mortality during follow-up. Of the 70 patients with complete follow-up, 24 patients (34.33%) had a 1-2 mm rVSD patch leak and 4 patients (5.7%) had a 2-3 mm rVSD patch leak at the time of discharge. At 12-month follow-up echocardiography, 67 patients (95.7%) had no rVSD patch leak. Aortic and tricuspid valve regurgitation significantly improved from discharge to 12 months after surgery. The size of the patch leak did not affect patients' weight gain (<i>P</i> ≥ .05).ConclusionsWe demonstrated that a 2 mm or less rVSD patch leak is benign, has no impact on tricuspid or aortic valve function, no impact on weight gain, and almost always decreases in severity or disappears.

World Journal for Pediatric and Congenital Heart SurgeryVol. 16(5)
King Abdulaziz University (SA), King Saud bin Abdulaziz University for Health Sciences (SA), King Abdulaziz Medical City (SA), King Abdullah International Medical Research Center (SA), University of Jeddah (SA), Soliman Fakeeh Hospital (SA), National Guard Health Affairs (SA)
Good health and well-being
Openalex Percentile: Top 92%
Congenital Heart Disease Studies
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