Preoperative CT attenuation value classification assesses cage subsidence risk in 112 OLIF surgery cases

Retrospective Study. This study investigates the effectiveness of preoperative vertebral computed tomography (CT) attenuation value classification in predicting cage subsidence in Oblique lumbar interbody fusion (OLIF) surgeries. This study aims to evaluate the feasibility of using CT attenuation value classification to predict cage subsidence. A retrospective analysis of L4-5 OLIF surgeries from May 2019 to June 2022, with over one year of follow-ups, was performed. Patients were classified into subsidence and non-subsidence groups based on postoperative outcomes. Demographic and perioperative variables, preoperative CT attenuation values, and changes in Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) scores were compared. Of 112 patients (29 in the subsidence group, 83 in the non-subsidence group), significant differences in gender (P = 0.032) and DXA T-value (P = 0.010) were noted, with the subsidence group predominantly female. The consistency of CT attenuation values across L1-L5 vertebral bodies demonstrated strong reliability, with intraclass correlation coefficient (ICC) ranging from 0.76 to 0.91. CT attenuation values, categorized into osteoporosis, osteopenia, and regular bone mass groups, correlated significantly with bone density and subsidence, especially at the L1 vertebra (r = 0.548, P < 0.001). Multivariate logistic regression confirmed the predictive value of vertebral CT stratification, with L1-L5 Odds Ratios (OR) ranging from 0.07 to 0.26. Females are more prone to OLIF-related cage subsidence. The measurement of CT attenuation values demonstrated strong reliability and consistency. Preoperative vertebral CT attenuation value classification correlates with bone density and subsidence risk, particularly at the L1 vertebra, and strongly predicts cage subsidence.

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Publication Details

Journal
Scientific Reports
Published
2025-03-25
DOI
https://doi.org/10.1038/s41598-025-94696-6
Citations
3
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
Field-Weighted Citation Impact
4.56
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Preoperative CT attenuation value classification assesses cage subsidence risk in 112 OLIF surgery cases

Zelin Zhou, Xiaobing Jiang, De Liang, Wanyan Chen et al.
3 citations
Scientific Reports
Cerebrovascular and Carotid Artery Diseases
4.56
article

Preoperative CT attenuation value classification assesses cage subsidence risk in 112 OLIF surgery cases

Zelin Zhou, Xiaobing Jiang, De Liang, Wanyan Chen, Xingda Chen, Zefeng Song, Jingjing Tang, Riwei Tan, Guangye Zhu, Hui Ren, Rueishiuan Jiang, Guohua Liang
article en
3 citations

Abstract

Retrospective Study. This study investigates the effectiveness of preoperative vertebral computed tomography (CT) attenuation value classification in predicting cage subsidence in Oblique lumbar interbody fusion (OLIF) surgeries. This study aims to evaluate the feasibility of using CT attenuation value classification to predict cage subsidence. A retrospective analysis of L4-5 OLIF surgeries from May 2019 to June 2022, with over one year of follow-ups, was performed. Patients were classified into subsidence and non-subsidence groups based on postoperative outcomes. Demographic and perioperative variables, preoperative CT attenuation values, and changes in Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) scores were compared. Of 112 patients (29 in the subsidence group, 83 in the non-subsidence group), significant differences in gender (P = 0.032) and DXA T-value (P = 0.010) were noted, with the subsidence group predominantly female. The consistency of CT attenuation values across L1-L5 vertebral bodies demonstrated strong reliability, with intraclass correlation coefficient (ICC) ranging from 0.76 to 0.91. CT attenuation values, categorized into osteoporosis, osteopenia, and regular bone mass groups, correlated significantly with bone density and subsidence, especially at the L1 vertebra (r = 0.548, P < 0.001). Multivariate logistic regression confirmed the predictive value of vertebral CT stratification, with L1-L5 Odds Ratios (OR) ranging from 0.07 to 0.26. Females are more prone to OLIF-related cage subsidence. The measurement of CT attenuation values demonstrated strong reliability and consistency. Preoperative vertebral CT attenuation value classification correlates with bone density and subsidence risk, particularly at the L1 vertebra, and strongly predicts cage subsidence.

Scientific ReportsVol. 15(1)
Guangzhou University of Chinese Medicine (CN), Nanjing University of Chinese Medicine (CN), Dalian University of Technology (CN), Second Affiliated Hospital of Guangzhou Medical University (CN), First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN), Guangzhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 6%
Cerebrovascular and Carotid Artery Diseases
4.56
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