Comparing the effect of using calcified autogenous nano dentin particles versus micro dentin particles in the healing of mandibular bony defects in New Zealand rabbits

Nano-dentin significantly enhanced bone density and defect closure, as evidenced by CBCT and histological analyses. At eight weeks, it promoted extensive new bone formation, nearly bridging the defect, with minimal residual graft material compared to the micro-dentin group. Histomorphometric analysis confirmed its superior osteogenic potential, demonstrating enhanced bone regeneration and graft resorption. These findings highlight nano-dentin as a highly effective biomaterial for mandibular bone repair.