Characterization of Mass Spectrometry Fragmentation Patterns Under Electron‐Activated Dissociation (EAD) for Rapid Structure Identification of Nitazene Analogs
The fragmentation pathways of the main fragment ions were elucidated based on the EAD-MS<sup>2</sup> spectra. Based on the summarized mass spectrometry characteristics of nitazene analogs, a flowchart was developed to guide the structure prediction of novel nitazene derivatives encountered in forensic casework. EAD was recognized as a perfect technique for accurate structure prediction and identification of new emerging nitazene analogs.
Authors
- Cuimei Liu
- Boxian Huang (ORCID: https://orcid.org/0000-0001-9913-9077)
- Zhiyu Li (ORCID: https://orcid.org/0000-0001-6492-9511)
- Wei Jia (ORCID: https://orcid.org/0000-0002-3739-8994)
- Zhendong Hua
Institutions
- Ministry of Public Security of the People's Republic of China (CN)
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Rapid Communications in Mass Spectrometry
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1002/rcm.10030
- Citations
- 7
- Primary Topic
- Forensic Toxicology and Drug Analysis
- Type
- article
- Field-Weighted Citation Impact
- 9.15
Funders
- National Key Research and Development Program of China