H3K27M-mutant spinal cord and hemispheric tumor with prolonged survival: illustrative case
The authors report the rare case of an adult-onset H3K27M midline glioma in the spinal cord and subsequent dissemination to the right temporal lobe with prolonged survival. This suggests that H3K27M-altered DMGs are heterogeneous entities with variable prognoses based on location and age. https://thejns.org/doi/10.3171/CASE24668.
Authors
- Kristen Marciniuk (ORCID: https://orcid.org/0000-0003-3176-775X)
- Daryl R. Fourney (ORCID: https://orcid.org/0000-0002-6567-3236)
- Roland N. Auer (ORCID: https://orcid.org/0000-0001-9044-3419)
- Braeden D. Newton (ORCID: https://orcid.org/0000-0001-5668-8623)
- Eva Liu (ORCID: https://orcid.org/0000-0002-1502-0915)
- Patrick Toyota (ORCID: https://orcid.org/0009-0000-3164-3218)
- Nicole Coote (ORCID: https://orcid.org/0000-0001-8742-4065)
- Hsuan Ming Su
Institutions
- University of Saskatchewan (CA)
Publication Details
- Journal
- Journal of Neurosurgery Case Lessons
- Published
- 2025-03-24
- DOI
- https://doi.org/10.3171/case24668
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00