Comparing Antidepressant Effects of Psilocybin-Assisted Psychotherapy in Individuals That Were Unmedicated at Initial Screening Versus Individuals Discontinuing Medications for Study Participation: Comparaison des effets antidépresseurs de la psychot
Comparable improvements were observed in depression and anxiety and symptoms between antidepressant discontinued and UAS patients. These findings contrast with and contribute to the growing literature on the effects of medication tapering leading up to PAP. Further clinical research is needed to directly compare efficacy across medication statuses, in addition to evaluating psychedelic effects in individuals continuing antidepressants during PAP.
Authors
- Shakila Meshkat (ORCID: https://orcid.org/0000-0002-7010-1785)
- Danica E. Johnson (ORCID: https://orcid.org/0000-0003-2000-7691)
- Noah Chisamore (ORCID: https://orcid.org/0000-0003-3325-5854)
- Zoe Doyle (ORCID: https://orcid.org/0000-0002-0140-8994)
- Joshua D. Rosenblat (ORCID: https://orcid.org/0000-0002-4773-2191)
- Marc G. Blainey
- Jeremy Riva-Cambrin
- Ryan M. Brudner (ORCID: https://orcid.org/0009-0004-8381-7434)
- Erica Kaczmarek
- Roger S McIntyre
- Geneva Weiglein
Institutions
- University of Toronto (CA)
- Brain and Cognition Discovery Foundation (CA)
Publication Details
- Journal
- The Canadian Journal of Psychiatry
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1177/07067437251328316
- Citations
- 1
- Primary Topic
- Psychedelics and Drug Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.31