Cardiac arrhythmias of BCR-ABL inhibitors with or without triazole antifungal agents: A real-world pharmacovigilance study based on the food and drug administration adverse event reporting system database

BCR-ABL inhibitors plus triazole antifungal agents increase the risk of cardiac arrhythmia, particularly in the early stages of treatment, with the risk decreasing over time.

Authors

Lishan Lu
Rongrong Jia (ORCID: https://orcid.org/0000-0001-6868-9594)
Yixuan Tian
Xuemei Tian (ORCID: https://orcid.org/0000-0001-7920-3801)
Pu Bai
Peng Xie (ORCID: https://orcid.org/0000-0001-7499-1669)

Institutions

Inner Mongolia University of Science and Technology (CN)
Baotou Medical College (CN)
Inner Mongolia Medical University (CN)

Publication Details

Journal: SAGE Open Medicine
Published: 2025-03-25
DOI: https://doi.org/10.1177/20503121251328762
Primary Topic: Drug-Induced Adverse Reactions
Type: article
Field-Weighted Citation Impact: 0.00

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article

Cardiac arrhythmias of BCR-ABL inhibitors with or without triazole antifungal agents: A real-world pharmacovigilance study based on the food and drug administration adverse event reporting system database

Lishan Lu, Rongrong Jia, Yixuan Tian, Xuemei Tian et al.

Mar 25, 2025

2 links

SAGE Open Medicine

Drug-Induced Adverse Reactions

article

Cardiac arrhythmias of BCR-ABL inhibitors with or without triazole antifungal agents: A real-world pharmacovigilance study based on the food and drug administration adverse event reporting system database

Lishan Lu, Rongrong Jia, Yixuan Tian, Xuemei Tian, Pu Bai, Peng Xie

March 25, 2025article en

Abstract

BCR-ABL inhibitors plus triazole antifungal agents increase the risk of cardiac arrhythmia, particularly in the early stages of treatment, with the risk decreasing over time.

SAGE Open MedicineVol. 13

Inner Mongolia University of Science and Technology (CN), Baotou Medical College (CN), Inner Mongolia Medical University (CN)

Good health and well-being

Openalex Percentile: Top 93%

Drug-Induced Adverse Reactions

DOI Open Access PDF OpenAlex

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