The impact of cytoreductive surgery on outcomes in high tumor burden ovarian cancer after induction of PARP inhibitors

Following the introduction of PARPi, there was a trend toward improved PFS in patients with a higher Aletti_SCS who underwent R0 resection. These findings suggest that R0 resection may improve prognosis even in cases with a high tumor burden in the PARPi era.

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Publication Details

Journal
Journal of Gynecologic Oncology
Published
2025-01-01
DOI
https://doi.org/10.3802/jgo.2025.36.e91
Citations
3
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
5.09
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article

The impact of cytoreductive surgery on outcomes in high tumor burden ovarian cancer after induction of PARP inhibitors

Hiroyuki Kanao, Motoko Kanno, Shogo Nishino, Terumi Tanigawa et al.
3 citations
Journal of Gynecologic Oncology
Ovarian cancer diagnosis and treatment
5.09
article

The impact of cytoreductive surgery on outcomes in high tumor burden ovarian cancer after induction of PARP inhibitors

Hiroyuki Kanao, Motoko Kanno, Shogo Nishino, Terumi Tanigawa, Atsushi Fusegi, Naoki Miyazaki, Mayu Yunokawa
article en
3 citations

Abstract

Following the introduction of PARPi, there was a trend toward improved PFS in patients with a higher Aletti_SCS who underwent R0 resection. These findings suggest that R0 resection may improve prognosis even in cases with a high tumor burden in the PARPi era.

Journal of Gynecologic OncologyVol. 36(6)
The Cancer Institute Hospital (JP), Japanese Foundation For Cancer Research (JP)
Good health and well-being
Openalex Percentile: Top 6%
Ovarian cancer diagnosis and treatment
5.09
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The impact of cytoreductive surgery on outcomes in high tumor burden ovarian cancer after induction of PARP inhibitors — Hiroyuki Kanao, Motoko Kanno, et al. · Journal of Gynecologic Oncology (2025) | TGRS Research Map | TGRS