Shared Genomic Features Between Lung Adenocarcinoma and Type 2 Diabetes: A Bioinformatics Study
Our study elucidates the common mechanisms of immune response, TGF-β signaling pathway, and natural killer cells in LUAD and T2DM, and identifies <i>ATR</i>, <i>RFC4</i>, and <i>MCM2</i> as key potential biomarkers and therapeutic targets for the comorbidity of these two conditions.
Authors
- Sendaer Hailati (ORCID: https://orcid.org/0000-0001-5867-8744)
- Nulibiya Maihemuti (ORCID: https://orcid.org/0000-0002-8242-0062)
- Dilihuma Dilimulati (ORCID: https://orcid.org/0009-0004-9690-4350)
- Nuerbiye Nueraihemaiti
- Wenting Zhou (ORCID: https://orcid.org/0000-0003-2610-7634)
- Alhar Baishan
- Alifeiye Aikebaier
- Yipaerguli Paerhati
Institutions
- Xinjiang Medical University (CN)
- Xinjiang Technical Institute of Physics & Chemistry (CN)
Publication Details
- Journal
- Biology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3390/biology14040331
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China