Gene expression profiling of airway epithelium in <i>Mycobacterium avium</i> complex lung disease
<i>SLC26A4</i>, an anion exchanger, was markedly upregulated in MAC-LD AECs, alongside various immune-related genes. The associations between gene expression and key disease phenotypes suggest potential targets for novel therapeutics.
Authors
- Naoto Keicho (ORCID: https://orcid.org/0000-0001-8232-9448)
- Kozo Morimoto (ORCID: https://orcid.org/0000-0002-8239-9275)
- Akiko Miyabayashi
- Koji Furuuchi (ORCID: https://orcid.org/0000-0002-1208-7698)
- Kiyomi Shimoda
- Keiko Wakabayashi
- Tsutomu Yoshida (ORCID: https://orcid.org/0000-0002-2537-336X)
- Shintaro Seto (ORCID: https://orcid.org/0000-0001-8980-7377)
- Takayuki Nakagawa (ORCID: https://orcid.org/0000-0003-0603-8264)
- Miyako Hiramatsu
- Minako Hijikata (ORCID: https://orcid.org/0000-0002-1642-6597)
- Yuji Shiraishi
Institutions
- Japan Anti Tuberculosis Association (JP)
- Ibarakihigashi National Hospital (JP)
- Fukujuji Hospital (JP)
- SHOWA Medical University Fujigaoka Hospital (JP)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-03-25
- DOI
- https://doi.org/10.1183/23120541.00011-2025
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministry of Health, Labour and Welfare