Local Anesthetic Duration, Not Onset, Linked to MC1R Genotype in Redheads and Brunettes

To our knowledge there are no published studies that associate the effect of hair color with local anesthetic function on onset and duration of action via SNP genotyping. The SNP genotyping reaffirmed functional results, and points to the complimentary impact that precision medicine will have on clinical decision making and patient comfort with future studies to unravel the degree to which SNPs affect these responses.