Quadruple therapy with immunotherapy and chemotherapy as first-line conversion treatment for unresectable advanced gastric adenocarcinoma: A case report
To the best of our knowledge, this is the first reported case of unresectable locally advanced gastric adenocarcinoma successfully treated with quadruple therapy with a PD-1 inhibitor and chemotherapy as a first-line conversion regimen. This first-line conversion therapy with the quadruple regimen may be effective and safe for unresectable locally advanced gastric adenocarcinoma.
Authors
- Guochao Niu
- Wei Xu (ORCID: https://orcid.org/0000-0003-4208-7477)
- Ruifang Fan (ORCID: https://orcid.org/0009-0002-9765-4352)
- Liyuan Ma (ORCID: https://orcid.org/0000-0003-1589-7300)
- Yan Long (ORCID: https://orcid.org/0009-0001-0655-515X)
- WenQi Yao (ORCID: https://orcid.org/0000-0003-3924-1103)
- Zhipeng Lin (ORCID: https://orcid.org/0000-0001-9811-5436)
- Rui Xia (ORCID: https://orcid.org/0000-0001-5494-4232)
- Jianguo Ma (ORCID: https://orcid.org/0009-0007-5184-7550)
- Xiaoyu Du
- Shumei Xu
- Li-Wen Shen
Institutions
- Minzu University of China (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- 117th Hospital of People's Liberation Army (CN)
- Lanzhou Army General Hospital (CN)
- 181st Hospital of Chinese People's Liberation Army (CN)
Publication Details
- Journal
- World Journal of Gastrointestinal Oncology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.4251/wjgo.v17.i4.102258
- Citations
- 1
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 1.52