Increased <scp>IgG</scp> Levels at Diagnosis Are Associated With Worse Prognosis of Patients With Primary Biliary Cholangitis
This long-term study demonstrates that I-IgG levels characterise a subgroup of non-cirrhotic PBC patients with faster disease progression and increased probability of liver-related death. Normalisation of IgG levels during UDCA treatment seems to improve prognosis and therefore, these patients could benefit from stricter follow-up and earlier add-on second-line treatments.
Authors
- George Ν. Dalekos (ORCID: https://orcid.org/0000-0001-7075-8464)
- Stella Gabeta (ORCID: https://orcid.org/0000-0003-4779-8155)
- Vassiliki Lygoura
- Eirini I. Rigopoulou (ORCID: https://orcid.org/0000-0003-1978-4602)
- Nikolaos Gatselis (ORCID: https://orcid.org/0000-0002-3715-8640)
- George Giannoulis (ORCID: https://orcid.org/0000-0001-9651-7968)
Institutions
- University Hospital of Larissa (GR)
Publication Details
- Journal
- Liver International
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1111/liv.70074
- Citations
- 3
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 3.97
Funders
- Ipsen