Methods for determining the extent of ischemic changes in brain matter in the prognosis of clinical outcome after successful thromboextraction

The ASPECTS score, eASPECTS, the volume of brain matter with early CT signs of ischemic changes, the volume of brain matter with rCBF <30%, as well as the T<sub>max</sub>/rCBF mismatch value predict the outcome of the disease with a high degree of confidence within the timeframe from 0 to 16 hours. The ASPECTS score assessed by an expert doctor and the volume of the brain substance with rCBF <30% had the greatest prognostic value for the functional outcome. The volume with a T<sub>max</sub> >6 s had the least predictive value. Methods for assessing brain matter using artificial intelligence algorithms (eASPECTS and volume with early signs of ischemia) showed predictive value for the functional outcome comparable to the ASPECTS score obtained by radiologists on duty in routine practice.

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Publication Details

Journal
S S Korsakov Journal of Neurology and Psychiatry
Published
2025-03-21
DOI
https://doi.org/10.17116/jnevro202512503217
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Methods for determining the extent of ischemic changes in brain matter in the prognosis of clinical outcome after successful thromboextraction

Д. В. Скрыпник, К. Н. Журавлев, N. А. Shamalov, А. В. Костин et al.
S S Korsakov Journal of Neurology and Psychiatry
Acute Ischemic Stroke Management
article

Methods for determining the extent of ischemic changes in brain matter in the prognosis of clinical outcome after successful thromboextraction

Д. В. Скрыпник, К. Н. Журавлев, N. А. Shamalov, А. В. Костин, K. V. Anisimov, N. H. Gorst, А. B. Berdalin
article en

Abstract

The ASPECTS score, eASPECTS, the volume of brain matter with early CT signs of ischemic changes, the volume of brain matter with rCBF <30%, as well as the T<sub>max</sub>/rCBF mismatch value predict the outcome of the disease with a high degree of confidence within the timeframe from 0 to 16 hours. The ASPECTS score assessed by an expert doctor and the volume of the brain substance with rCBF <30% had the greatest prognostic value for the functional outcome. The volume with a T<sub>max</sub> >6 s had the least predictive value. Methods for assessing brain matter using artificial intelligence algorithms (eASPECTS and volume with early signs of ischemia) showed predictive value for the functional outcome comparable to the ASPECTS score obtained by radiologists on duty in routine practice.

S S Korsakov Journal of Neurology and PsychiatryVol. 125(3)
City Clinical Hospital (RU), Kharkiv Regional Clinical Psychiatric Hospital No 3 (UA)
No poverty
Openalex Percentile: Top 92%
Acute Ischemic Stroke Management
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Methods for determining the extent of ischemic changes in brain matter in the prognosis of clinical outcome after successful thromboextraction — Д. В. Скрыпник, К. Н. Журавлев, et al. · S S Korsakov Journal of Neurology and Psychiatry (2025) | TGRS Research Map | TGRS