Association of Circulating Cell‐Free Mitochondrial DNA With Sudden Sensorineural Hearing Loss
Plasma ccf-mtDNA levels were elevated in patients with SSNHL and were significantly associated with better treatment outcomes following steroid therapy. These findings suggest that ccf-mtDNA levels may serve as a predictive biomarker for SSNHL treatment outcomes, paving the way for personalized therapeutic strategies.
Authors
- Ming‐Hsien Tsai (ORCID: https://orcid.org/0000-0002-6877-1579)
- Wei‐Che Lin (ORCID: https://orcid.org/0000-0002-1326-0587)
- Ming‐Yu Yang (ORCID: https://orcid.org/0000-0002-6841-5478)
- I‐Ya Chen
- Yu‐Tsai Lin (ORCID: https://orcid.org/0000-0002-7311-8638)
- Chung‐Feng Hwang (ORCID: https://orcid.org/0000-0003-4126-5737)
- Ching‐Nung Wu (ORCID: https://orcid.org/0000-0001-9397-0986)
- Chao‐Hui Yang (ORCID: https://orcid.org/0000-0003-4055-1686)
Institutions
- National Sun Yat-sen University (TW)
- Chang Gung University (TW)
- Kaohsiung Chang Gung Memorial Hospital (TW)
- Kaohsiung Municipal Ta-Tung Hospital (TW)
Publication Details
- Journal
- Otolaryngology
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1002/ohn.1238
- Citations
- 1
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 1.46