Nature-inspired designing of KLR- and KLS-rich antimicrobial peptides: unleashing the antibiofilm potential of RbP12 against MDR <i>S. aureus</i> and <i>P. aeruginosa</i>
RbP12 was found to have higher antibacterial and antibiofilm activity against S. aureus P10 compared with P. aeruginosa PA64. With 96% cell viability, usage of RbP12 on human skin is totally safe. Based on these results, the aim is to develop self-assembled peptide hydrogels for wound healing in future work.
Authors
- S. Aslam
- Sidra Rahmat Ullah (ORCID: https://orcid.org/0000-0001-5426-4712)
- Muhammad Bilal Khan Niazi (ORCID: https://orcid.org/0000-0003-2781-404X)
- Saadia Andleeb (ORCID: https://orcid.org/0000-0002-0866-5993)
- Abdur Rahman (ORCID: https://orcid.org/0000-0002-0393-5384)
- Zeeshan Yaseen
Institutions
- King Fahd University of Petroleum and Minerals (SA)
- National University of Sciences and Technology (PK)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-03-24
- DOI
- https://doi.org/10.1093/jac/dkaf079
- Citations
- 2
- Primary Topic
- Antimicrobial Peptides and Activities
- Type
- article
- Field-Weighted Citation Impact
- 2.37
Funders
- National University of Sciences and Technology