The impact of inflammation on prostate tumor dynamics: a pathological perspective on prostate cancer and benign prostatic hyperplasia
This study emphasizes the importance of chronic inflammation in BPH development, with IL-8 and IL-6 playing essential roles. The results imply that treating BPH by focusing on IL-8 and IL-6 may be beneficial. Increased levels of FGF2 in PCa tissues suggest that this protein may be used as a biomarker and therapeutic target for PCa. These findings highlight the importance of targeting both inflammatory and growth factor pathways for treating prostatic disorders.
Authors
- Mochammad Hatta (ORCID: https://orcid.org/0000-0002-8456-4203)
- Syakri Syahrir (ORCID: https://orcid.org/0000-0001-9948-8250)
- Muhammad Asykar Palinrungi (ORCID: https://orcid.org/0000-0002-0135-9213)
- Syarif Syarif
- Muhammad Faruk (ORCID: https://orcid.org/0000-0002-7079-4585)
- Khoirul Kholis (ORCID: https://orcid.org/0000-0003-4841-6155)
- Abdul Azis (ORCID: https://orcid.org/0000-0002-4804-3208)
Institutions
- Muhammadiyah University of Makassar (ID)
- Hasanuddin University (ID)
Publication Details
- Journal
- Archivio Italiano di Urologia e Andrologia
- Published
- 2025-03-24
- DOI
- https://doi.org/10.4081/aiua.2025.13353
- Citations
- 2
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04