Factors Influencing Fluorescence-activated Cell Sorting for Multiple Myeloma Fluorescence <i>in situ</i> Hybridization: Real-world Experience
Plasma cell percentage and sample transfer time are critical factors influencing FACS success. While FACS-FISH demonstrates superior sensitivity in detecting CAs, direct FISH serves as a valuable alternative when FACS fails. These findings highlight the importance of optimizing sample handling and FISH protocols for accurate cytogenetic analysis of multiple myeloma.
Authors
- Jong Rak Choi (ORCID: https://orcid.org/0000-0002-0608-2989)
- Seung‐Tae Lee (ORCID: https://orcid.org/0000-0003-1047-1415)
- Kyunghee Yu (ORCID: https://orcid.org/0000-0002-6493-0683)
- Saeam Shin (ORCID: https://orcid.org/0000-0003-1501-3923)
- Jaeguk Choi (ORCID: https://orcid.org/0009-0001-4812-3574)
Institutions
- Yonsei University (KR)
- Severance Hospital (KR)
Publication Details
- Journal
- Annals of Laboratory Medicine
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3343/alm.2024.0582
- Citations
- 1
- Primary Topic
- Multiple Myeloma Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.77