Dynamics of changes in sturgeon blood biochemical parameters under the influence of polymer systems with fluoroquinolone

In the process of growing aquatic organisms in industrial conditions, specialists face various difficulties, including fish diseases. In this regard, the use of polymer systems with fluoroquinolone, characterized by the bioavailability of substances, contributes to the targeted suppression and destruction of bacterial microflora, as well as to the improvement of the productive indicators of aquatic organisms. The article presents information on the possibility of using polymer systems with fluoroquinolone and their effect on the biochemical parameters of the blood serum of sturgeon fish. During the experiment, the following parameters were studied: direct and total bilirubin, total protein, aminotransferases, alkaline phosphatase, creatinine, glucose and macroelements. Analyses were taken on the 8th and 14th days of the experiment from three specimens from all experimental groups. The effect of the polymer system with levofloxacin on hybrid sturgeon specimens was studied in the laboratory of “Progressive Biotechnology in Aquaculture” of Vavilov University. The results of the analysis demonstrate that on the 8th day, a change in most biochemical parameters of the blood is observed (change in the amount of total protein, bilirubin content, aminotransferase activity), which is associated with the injury of the fish and the receipt of polymer systems with fluoroquinolone, which are an additional stress factor for the body of aquatic organisms. By the 14th day, the wounds are scarred, after 8 days the course of application of nanocomplexes with antibiotics is completed, respectively, the physiological state of the fish and biochemical blood parameters are normalized. The results obtained expand information on the cultivation of sturgeon fish in industrial conditions using polymer systems for the delivery of fluoroquinolone antibiotics.