Design, Synthesis, and Evaluation of Cytotoxic Effects of Functional Fatty Acid Derivatives as Potential Antineoplastic Agents for Breast Cancer
The findings indicate that these functional fatty acid derivatives significantly reduce cancer cell viability. In addition to necrosis, compounds L3 and D3 induced apoptosis, with apoptosis rates of 20.5% and 47.1%, respectively.
Authors
- Farzad Kobarfard (ORCID: https://orcid.org/0000-0001-6679-3275)
- Salimeh Amidi (ORCID: https://orcid.org/0000-0002-6032-3237)
- Anna Sedaghat (ORCID: https://orcid.org/0000-0001-8042-2948)
- Maryam Hosseini (ORCID: https://orcid.org/0000-0002-7482-6185)
- Shaya Mokhtari (ORCID: https://orcid.org/0000-0002-8548-6585)
- Soraya Shahhosseini
Institutions
- Oslo University Hospital (NO)
- Iran University of Medical Sciences (IR)
- University of Oslo (NO)
- Shahid Beheshti University of Medical Sciences (IR)
Publication Details
- Journal
- Iranian journal of pharmaceutical research
- Published
- 2025-03-15
- DOI
- https://doi.org/10.5812/ijpr-159523
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00