Patterns, Predictors, and Prognostic Implication of Treatment-Related Amenorrhea in Patients With Breast Cancer
Age > 45 years and the usage of hormonal therapy are risk factors for LA, while metastatic disease was associated with a decreased risk. Both EA and LA had a significant association with favorable 3-year OS. These findings enable clinicians to provide personalized guidance, tailor treatment strategies, and improve the outcomes of premenopausal patients with breast cancer. Standardization of how TRA is defined and assessed in future studies is essential to improve comparability and enhance the understanding of its clinical implications.
Authors
- Wigati Dhamiyati (ORCID: https://orcid.org/0000-0003-3952-9502)
- Juan Adrian Wiranata (ORCID: https://orcid.org/0000-0002-4093-6327)
- Yufi Kartika Astari (ORCID: https://orcid.org/0000-0003-0999-8826)
- Kartika Widayati Taroeno‐Hariadi (ORCID: https://orcid.org/0000-0002-7791-9010)
- Irianiwati Widodo (ORCID: https://orcid.org/0000-0002-0346-0550)
- Susanna Hilda Hutajulu (ORCID: https://orcid.org/0000-0001-9236-9435)
- Suwardjo Suwardjo (ORCID: https://orcid.org/0000-0002-0484-7773)
- Lina Choridah (ORCID: https://orcid.org/0000-0002-0917-9372)
- Bryant Ng (ORCID: https://orcid.org/0009-0003-1218-8063)
- Mardiah Suci Hardianti (ORCID: https://orcid.org/0000-0002-5360-6693)
- Armeyra Devani Ferintasari
Institutions
- Universitas Gadjah Mada (ID)
- Rumah Sakit Umum Pusat Dr. Sardjito (ID)
Publication Details
- Journal
- World Journal of Oncology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.14740/wjon1991
- Citations
- 1
- Primary Topic
- Cancer Risks and Factors
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Universitas Gadjah Mada
- Pázmány Péter Katolikus Egyetem