Performance of fasting plasma glucose for community-based screening of undiagnosed diabetes and pre-diabetes in sub-Saharan Africa
FPG was able to correctly identify 99.3% of individuals with no diabetes but a significant percentage of diabetes cases would have remained undiagnosed if only FPG had been utilized instead of the 2-h PG. The use of 2-h PG test is recommended to diagnose diabetes in older individuals, females and non-obese persons who would be missed if tested by only FPG. Lowering the cut-off value for FPG to 105 mg/dL substantially increases the identification of individuals with diabetes, thus improving the effectiveness of FPG as a screening test for type 2 diabetes.
Authors
- Suvi Karuranga
- Assefa Mulu Baye (ORCID: https://orcid.org/0000-0002-6657-7828)
- Ifeoma Isabella Ulasi
- Ekenechukwu Young (ORCID: https://orcid.org/0000-0002-2926-8524)
- Adem Y. Dawed (ORCID: https://orcid.org/0000-0003-0224-2428)
- Teferi Gedif Fenta (ORCID: https://orcid.org/0000-0001-8500-6708)
- Ifeyinwa Dorothy Nnakenyi (ORCID: https://orcid.org/0000-0002-4771-4241)
- Ewan R. Pearson (ORCID: https://orcid.org/0000-0001-9237-8585)
Institutions
- University of Dundee (GB)
- Ninewells Hospital (GB)
- Genomics (United Kingdom) (GB)
- Federal Teaching Hospital Abakaliki (NG)
- University of Nigeria Teaching Hospital (NG)
- Addis Ababa University (ET)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-03-25
- DOI
- https://doi.org/10.3389/fendo.2025.1501383
- Citations
- 1
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 1.29