Inhalable exosomes to target cardiac repair

A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This approach improves cardiac function, reduces injury, and demonstrates translational potential in both small and large animal models, offering a promising avenue for cell-free, inhalable regenerative therapies.

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Publication Details

Journal
Extracellular Vesicles and Circulating Nucleic Acids
Published
2025-03-25
DOI
https://doi.org/10.20517/evcna.2024.81
Citations
5
Primary Topic
Extracellular vesicles in disease
Type
article
Field-Weighted Citation Impact
4.03
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article

Inhalable exosomes to target cardiac repair

Ajit Magadum
5 citations
Extracellular Vesicles and Circulating Nucleic Acids
Extracellular vesicles in disease
4.03
article

Inhalable exosomes to target cardiac repair

Ajit Magadum
article en
5 citations

Abstract

A recent study introduces Stem Cell-derived Exosome Nebulization Therapy (SCENT), a novel, non-invasive strategy that delivers lung spheroid cell-derived exosomes via inhalation to promote cardiac repair after myocardial infarction. This approach improves cardiac function, reduces injury, and demonstrates translational potential in both small and large animal models, offering a promising avenue for cell-free, inhalable regenerative therapies.

Extracellular Vesicles and Circulating Nucleic AcidsVol. 6(1)
University of South Florida (US), Temple University (US)
Good health and well-being
Openalex Percentile: Top 7%
Extracellular vesicles in disease
4.03
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