Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

<i>RAC1</i> and <i>CMTM5</i> are differentially expressed in the frontal lobes of BCAS mice, suggesting their potential as biomarkers for diagnosing and prognosis of VaD. These findings pave the way for exploring novel molecular mechanisms aimed at preventing or treating VaD.

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Publication Details

Journal
Frontiers in Immunology
Published
2025-03-24
DOI
https://doi.org/10.3389/fimmu.2025.1560438
Citations
2
Primary Topic
Neurological Disease Mechanisms and Treatments
Type
article
Field-Weighted Citation Impact
1.68
Controls
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article

Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

Yilong Zhao, Yilong Wang, Weiqi Chen, Wen Xing
2 citations
Frontiers in Immunology
Neurological Disease Mechanisms and Treatments
1.68
article

Integrated bioinformatics analysis and biological experiments to identify key immune genes in vascular dementia

Yilong Zhao, Yilong Wang, Weiqi Chen, Wen Xing
article en
2 citations

Abstract

<i>RAC1</i> and <i>CMTM5</i> are differentially expressed in the frontal lobes of BCAS mice, suggesting their potential as biomarkers for diagnosing and prognosis of VaD. These findings pave the way for exploring novel molecular mechanisms aimed at preventing or treating VaD.

Frontiers in ImmunologyVol. 16
Capital Medical University (CN), Chinese Academy of Sciences (CN), China Rehabilitation Research Center (CN), Beijing Tian Tan Hospital (CN), National Clinical Research Center for Digestive Diseases (CN), Institute of Biophysics (CN), Chinese Institute for Brain Research (CN), University of Chinese Academy of Sciences (CN)
Good health and well-being
Openalex Percentile: Top 17%
Neurological Disease Mechanisms and Treatments
1.68
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