Proposal of a New Therapeutic Approach for Adult Atypical Teratoid/Rhabdoid Tumor Based on Literature Review and Case Report
Rhabdoid tumors are aggressive soft tissue sarcomas predominantly affecting children under three years of age. While rare, cases of Atypical Teratoid/Rhabdoid Tumors (AT/RT) have been reported in adults, presenting unique challenges for treatment. This article presents a new therapeutic approach for adult AT/RT based on a case report and literature review. The case involves an adult male diagnosed with AT/RT who achieved a ten-year survival through a comprehensive treatment regimen. The approach includes surgical resection, intensive chemotherapy, and radiation therapy. The study highlights the importance of adopting an intensive chemotherapy protocol, typically used in pediatric cases, as a promising strategy for adult AT/RT management. This innovative proposal underscores the need for further research and therapeutic advancements to improve outcomes in this rare disease.
Authors
- Maxime Rivollier (ORCID: https://orcid.org/0000-0001-8496-0532)
- Philippe Colin (ORCID: https://orcid.org/0000-0002-5552-8908)
- Claude‐Fabien Litré
- Jean‐Charles Kleiber
- Nathan Gaquere
Publication Details
- Journal
- Voice of the Publisher
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4236/vp.2025.111013
- Primary Topic
- Chromatin Remodeling and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00