Proposal of a New Therapeutic Approach for Adult Atypical Teratoid/Rhabdoid Tumor Based on Literature Review and Case Report

Rhabdoid tumors are aggressive soft tissue sarcomas predominantly affecting children under three years of age. While rare, cases of Atypical Teratoid/Rhabdoid Tumors (AT/RT) have been reported in adults, presenting unique challenges for treatment. This article presents a new therapeutic approach for adult AT/RT based on a case report and literature review. The case involves an adult male diagnosed with AT/RT who achieved a ten-year survival through a comprehensive treatment regimen. The approach includes surgical resection, intensive chemotherapy, and radiation therapy. The study highlights the importance of adopting an intensive chemotherapy protocol, typically used in pediatric cases, as a promising strategy for adult AT/RT management. This innovative proposal underscores the need for further research and therapeutic advancements to improve outcomes in this rare disease.

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Publication Details

Journal
Voice of the Publisher
Published
2025-01-01
DOI
https://doi.org/10.4236/vp.2025.111013
Primary Topic
Chromatin Remodeling and Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Proposal of a New Therapeutic Approach for Adult Atypical Teratoid/Rhabdoid Tumor Based on Literature Review and Case Report

Maxime Rivollier, Philippe Colin, Claude‐Fabien Litré, Jean‐Charles Kleiber et al.
Voice of the Publisher
Chromatin Remodeling and Cancer
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Proposal of a New Therapeutic Approach for Adult Atypical Teratoid/Rhabdoid Tumor Based on Literature Review and Case Report

Maxime Rivollier, Philippe Colin, Claude‐Fabien Litré, Jean‐Charles Kleiber, Nathan Gaquere
article en

Abstract

Rhabdoid tumors are aggressive soft tissue sarcomas predominantly affecting children under three years of age. While rare, cases of Atypical Teratoid/Rhabdoid Tumors (AT/RT) have been reported in adults, presenting unique challenges for treatment. This article presents a new therapeutic approach for adult AT/RT based on a case report and literature review. The case involves an adult male diagnosed with AT/RT who achieved a ten-year survival through a comprehensive treatment regimen. The approach includes surgical resection, intensive chemotherapy, and radiation therapy. The study highlights the importance of adopting an intensive chemotherapy protocol, typically used in pediatric cases, as a promising strategy for adult AT/RT management. This innovative proposal underscores the need for further research and therapeutic advancements to improve outcomes in this rare disease.

Voice of the PublisherVol. 11(01)
Openalex Percentile: Top 95%
Chromatin Remodeling and Cancer
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